CALCIUM PHOSPHATE-BASED BIOMATERIAL CONTAINING CALCIUM CARBONATE
(11)Publication number : |
2003-300806 |
(43)Date of publication of application : |
21.10.2003 |
(51)Int.CI. |
A61K 6/033
A61K 6/08
A61L 27/00
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(21)Application number : |
2002-110287 |
(71)Applicant : |
MARUO CALCIUM CO LTD
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(22)Date of filing : |
12.04.2002 |
(72)Inventor : |
KON MASAYUKI
ASAOKA KENZO
LUCIANA M HIRAKATA
MIYAMOTO YOJI
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Abstract:
PROBLEM TO BE SOLVED: To provide a calcium phosphate-based biomaterial excellent in mechanical properties, an affinity for organisms and biofunctional properties (e.g. osseous conduction ability).
SOLUTION: This calcium phosphate-based biomaterial
comprises a calcium phosphate-based compound containing calcium
carbonate having 1-50 aspect ratio (crystal length/crystal width).
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COMPOUND BIOMATERIAL CONTAINING PHOSPHO-FOLIN
(11)Publication number : |
2003-235953 |
(43)Date of publication of application : |
26.08.2003 |
(21)Application number : |
2002-041409 |
(71)Applicant : |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY
|
(22)Date of filing : |
19.02.2002 |
(72)Inventor : |
UEMURA JIYUKO
TATEISHI TETSUYA
SAITO TAKASHI
IESHIMA DAISUKE
|
Abstract:
PROBLEM TO BE SOLVED: To obtain a low-priced artificial bone material
having an excellent bioadaptability and the bone forming ability (bone
formation inducing ability).
SOLUTION: This artificial bone material is obtained by culturing a bone marrow-derived cell on a compound biomaterial having a sponge structure containing phospho-folin and collagen.
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ARTIFICIAL BIOMATERIAL
(11)Publication number : |
2003-220127 |
(43)Date of publication of application : |
05.08.2003 |
(51)Int.CI. |
A61L 27/00
// C01G 23/04
|
(21)Application number : |
2002-022310 |
(71)Applicant : |
CHUBU ELECTRIC POWER CO INC
|
(22)Date of filing : |
30.01.2002 |
(72)Inventor : |
KASUGA TOMOKO
MASUI KAZUNORI
HIRAMATSU MASAYOSHI
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Abstract:
PROBLEM TO BE SOLVED: To provide artificial biomaterials having a high
biological activity and ability to be bonded with natural bones in a
shorter period compared with conventional materials.
SOLUTION:
These artificial biomaterials are composed entirely or mainly of a
nanotube body comprising titanium oxide and/or titanium oxide based
double oxides. In particular, the material carrying a metal ion such as
calcium ion thereon is excellent in the bone-forming ability.
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BIOMATERIAL FOR ARTIFICIAL CARTILAGE AND ITS MANUFACTURING METHOD
(11)Publication number : |
2003-210499 |
(43)Date of publication of application : |
29.07.2003 |
(51)Int.CI. |
A61F 2/38
A61F 2/44
A61L 27/00
|
(21)Application number : |
2002-013674 |
(71)Applicant : |
TAKIRON CO LTD
|
(22)Date of filing : |
23.01.2002 |
(72)Inventor : |
TSUTA KAORU
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Abstract:
PROBLEM TO BE SOLVED: To provide biomaterial for an artificial cartilage and a method of manufacturing the biomaterial
showing deformation behavior approximate to a cartilage, describing a
J-type stress-strain curve when compressive force and tensile force are
applied thereto.
SOLUTION: This biomaterial
1 for the artificial cartilage is formed of a triaxial and
three-dimensional woven texture body woven and knitted with organic
yarn and constituted by laminating V-axis yarn array layers 2 formed of
endless folding arrangement of V-axis yarn 2 meandering in an oblique
V-axis direction to an X-axis and a Y-axis within an X-Y plane, and
W-axis yarn array layers 3 formed of endless folding arrangement of
W-axis yarn 3a meandering in a reverse oblique W-axis direction,
alternately in multilayers in a Z-axis direction, and
caulking-connecting the array layers 2, 3 by Z-axis yarn 4a of endless
folding arrangement piercingly meandering in the Z-direction. The biomaterial
may be formed of a four-axis and three-dimensional woven texture body
formed by laminating the V-axis yarn array layers, the W-axis yarn
array layers, and X-axis yarn array layers or Y-axis yarn array layers
of endless folding arrangement meandering in an X-axis or Y-axis
direction, alternately in multilayers and caulking-connecting them by
Z-axis yarn. Such a biomaterial is
manufactured by a manufacturing method comprising a laminating process
of the array layers, a clamping process and a caulking-connecting
process by the Z-axis yarn.
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BIOMATERIAL AND METHOD OF MANUFACTURING THE SAME
(11)Publication number : |
2002-369875 |
(43)Date of publication of application : |
24.12.2002 |
(21)Application number : |
2001-180924 |
(71)Applicant : |
YAMASHITA KIKUJI
YAMASHITA TAKAHIRO
|
(22)Date of filing : |
15.06.2001 |
(72)Inventor : |
YAMASHITA KIKUJI
|
Abstract:
PROBLEM TO BE SOLVED: To provide a biomaterial
which has calcification ability, has high bioaffinity and strength, is
usable for living organism and is easily disposable when used for other
purposes than for the living organisms and a method of manufacturing
the same.
SOLUTION: This material is used by being embedded into
the living organism and is composed by forming a layer 13 of a calcium
compound on the surface of a foundation material 10 and bonding
crosslinked collagen 14 to the surface of a layer of the calcium
compound of the foundation material 10. Even if, therefore, the
foundation material 10 is any material, the bioaffinity can be
improved. Even more, the crosslinked collagen 14 is bonded to the
surface of the layer 13 of the calcium compound and since the
bioaffinity of the biomaterial 1 can be
thereby further enhanced, the adverse influence to be exerted on the
living organism when the material is embedded into the living organism
can be prevented.
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CROSSLINKING COMPOSITE BIOMATERIAL
(11)Publication number : |
2002-143290 |
(43)Date of publication of application : |
21.05.2002 |
(51)Int.CI. |
A61L 15/64
A61L 27/00
|
(21)Application number : |
2000-349084 |
(71)Applicant : |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY
|
(22)Date of filing : |
16.11.2000 |
(72)Inventor : |
CHIN KUNIHEI
TATEISHI TETSUYA
USHIDA TAKASHI
|
Abstract:
PROBLEM TO BE SOLVED: To obtain a new crosslinking composite biomaterial
which exhibits excellent bioabsorbability and biocompatibility, is
excellent in dissemination of cells and clinical handling property, has
enough mechanical strength, is useful for regenerating or restructuring
a covering material for skin wound such as skin ulcer and burn, or a
skin tissue or living tissue or an internal organ such as ligament,
bronchi and intestials, and provide an advantageous method for
manufacturing the crosslinking composite biomaterial.
SOLUTION: This biomaterial
comprises a bioabsorbable synthetic polymer mesh body and a
tissue-derived natural polymer porous body. The mesh body is made of a
cloth, a woven fabric or an unwoven fabric, and a bioabsorbable
synthetic polymer is formed from polylactic acid, polyglycolic acid or
a copolymer of lactic acid with glycolic acid. The tissue-derived
natural polymer is at least one kind selected from among collagen,
gelatin, fibronectin or laminin. After treated in a tissue-derived
natural polymer solution, the mesh body is freeze-dried, and the
generated composite biomaterial is treated with a gaseous chemical crosslinking agent.
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METHOD FOR MANUFACTURING POROUS INTERMETALLIC COMPOUND OR CERAMICS
(11)Publication number : |
2002-097531 |
(43)Date of publication of application : |
02.04.2002 |
(51)Int.CI.
C22C 1/08 B22F 3/11 C04B 38/00 C22C 1/10
|
(21)Application number : |
2000-291508 |
(71)Applicant : |
JAPAN SCIENCE & TECHNOLOGY CORP
|
(22)Date of filing : |
26.09.2000 |
(72)Inventor : |
KANETAKE NAOYUKI
KOBASHI MAKOTO
CHO TAKAO
|
Abstract:
PROBLEM TO BE SOLVED: To provide porous intermetallic compounds or
ceramics useful for a filter for cleaning waste gas, an impact
absorption member, a heat insulating and sound absorbing material, biomaterial and the like.
SOLUTION:
This method for manufacturing the porous intermetallic compounds or
ceramics comprises mixing different kinds of metal powders according to
a composition in manufacturing the intermetallic compounds or the
ceramics, forming them with combustion synthesis, and making them
porous by means of generating bubbles of gas components absorbed or
occluded in the metal powders, during the combustion synthesis. Pore
size or porosity of the porous intermetallic compound or the ceramics
is controlled by a mixing rate of a raw material powder, a compression
ratio of the mixed powders, a heat quantity on preheating and the
combustion synthesis, and an addition of exothermic or endothermic
auxiliaries.
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